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Taking ephedrine with hydrocortisone can lower the amount of hydrocortisone in your body and decrease its effect. If you start or stop taking it while taking hydrocortisone, your doctor may need to change your dosage of hydrocortisone.

Check with your doctor before getting any vaccines. You should not receive live vaccines if you take high doses of hydrocortisone or have been taking hydrocortisone for a long time. Examples of live vaccines include:. Examples of these vaccines include:. Taking warfarin with hydrocortisone may increase or decrease the blood-thinning effects of warfarin. Your dosage may need to be adjusted by your doctor.

You may be at a higher risk of ulcers and bleeding. However, because drugs interact differently in each person, we can not guarantee that this information includes all possible interactions.

Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Taking it again could be fatal cause death.

If you get measles or chickenpox, you may have a severe case that can be fatal cause death. During your treatment with this drug and for up to 12 months after, call your doctor right away if you:. For people with infections: This medication can cover up mask symptoms of infection. It can also make it harder for your body to fight an infection. For people with high blood pressure: Hydrocortisone can raise your blood pressure.

Use it with caution if you have high blood pressure or heart problems. Monitor your blood pressure more closely while you take hydrocortisone. For people with diabetes: Hydrocortisone can increase your blood sugar levels. For people with glaucoma: Hydrocortisone can increase the pressure in your eyes. This may make your glaucoma worse. Your doctor may check your eyes regularly if you take this medication.

For people with stomach or intestinal problems: Hydrocortisone can irritate your stomach or intestines, which can worsen your stomach or intestinal problems. For people with liver problems: Hydrocortisone is broken down in your liver. If you have severe liver disease, it may build up in your body and have dangerous effects.

You may need a lower dosage of this medication. For people with thyroid problems: If you have low thyroid function, you may be more sensitive to the effects of hydrocortisone. For people with mental health problems: Hydrocortisone can worsen mood changes, personality changes, depression, and hallucinations. You may need dosage adjustments of your mental health medications. For people with congestive heart failure: Hydrocortisone makes your body retain water and salt, which can make heart failure worse.

You may need to eat a low-salt diet. Your heart medication dosage may need to be changed. For people with Cushing syndrome: People with this condition already have too much steroid hormone in their body.

Taking hydrocortisone, a steroid hormone, can worsen symptoms of Cushing syndrome. For people with low potassium: Hydrocortisone may increase the amount of potassium that leaves your body in your urine. Your risk is higher if you take high doses of the drug. Your doctor will check your potassium levels while you take hydrocortisone. You may need to take potassium supplements.

For people with ocular herpes simplex: If you have ocular herpes simplex, use this drug with caution. It may increase your risk for perforation or small holes in the outer layer of your eye called the cornea.

For pregnant women: Taking hydrocortisone while you are pregnant may harm your pregnancy. Hydrocortisone should be used during pregnancy only if the potential benefit justifies the potential risk. For women who are breastfeeding: Taking hydrocortisone while you are breastfeeding may harm your breastfed child. You may need to decide whether to stop breastfeeding or stop taking hydrocortisone.

It may also increase your risk of developing osteoporosis. For children: Hydrocortisone can delay growth and development in children and infants. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:.

It will depend on factors such as the condition being treated and how severe it is. The serious side effects of dosulepin can be made worse by binge drinking. If you're drinking alcohol with dosulepin, it's best to cut down the amount you drink. Dosulepin does not affect any type of contraception, including the combined pill or emergency contraception. The good effects of dosulepin may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again.

Sexual side effects are not common and should pass after the first couple of weeks. If they don't and this is a problem for you, go back to your doctor to see if there's another antidepressant you can try. If you're a woman and you get vaginal bleeding after the menopause , make an appointment to see your doctor as soon as possible. There's no firm evidence to suggest that taking dosulepin will reduce fertility in either men or women. However, speak to a pharmacist or your doctor before taking it if you're trying to get pregnant.

Cannabis with dosulepin can make you feel very sleepy, especially if you have just started taking it. Cannabis with dosulepin can also give you a fast heartbeat. Dosulepin hasn't been properly tested with recreational drugs. Talk to your doctor if you think you might use recreational drugs while taking dosulepin.

Antidepressants, including dosulepin, are just one of several approaches to treating depression. Other potential treatments include:. If you're interested in any of these treatments, talk to your doctor.

Page last reviewed: 13 December Next review due: 13 December Dosulepin On this page About dosulepin Key facts Who can and can't take dosulepin How and when to take it Side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions.

About dosulepin Dosulepin is an antidepressant medicine. It comes as capsules and tablets. Help us improve our website Can you answer a quick question about your visit today? Dosulepin was commonly used as an antidepressant in the past.

But these days doctors don't write new prescriptions for it unless it has been recommended by a specialist because of concerns about side effects. If you're already taking dosulepin, your doctor will want to consider whether it's still the best treatment option for you. They'll only continue to prescribe dosulepin if a consultant or another specialist agrees with this decision.

Common side effects include constipation, feeling dizzy, a dry mouth, feeling sleepy, difficulty peeing, or headaches. Dosulepin can cause extra side effects if you stop taking it suddenly. Talk to your doctor if you're thinking of stopping taking dosulepin. Dosulepin is also known as dothiepin or by the brand name Prothiaden. Check with your doctor if you: have had an allergic reaction to dosulepin or any other medicine in the past have a heart problem — dosulepin can make some heart problems worse have a rare illness called porphyria have liver or kidney problems have epilepsy or are having electroconvulsive treatment — dosulepin may increase your risk of having a seizure have an eye problem called glaucoma — dosulepin can increase the pressure in your eye have thoughts about harming yourself or ending your life are trying to become pregnant, are already pregnant or are breastfeeding If you have diabetes , dosulepin may change your blood sugar level.

Dosage Dosulepin comes in 2 different strengths — either 25mg capsules or 75mg tablets. What if I forget to take it? Never take 2 doses at the same time to make up for a forgotten one. What if I take too much? Urgent advice: Call your doctor now if:. Call your doctor straight away, even if you don't have any symptoms. Common side effects Some of the common side effects gradually improve as your body gets used to dosulepin.

Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don't go away: constipation dizziness a dry mouth feeling sleepy, tired or weak difficulty peeing headaches Serious side effects It happens rarely, but some people have serious side effects after taking dosulepin.

Call a doctor now if you get: a fast or irregular heartbeat yellow skin, or the whites of your eyes go yellow — these can be signs of a liver problem constant headaches, long-lasting confusion or weakness, or frequent muscle cramps — these can all be signs of low sodium levels in your blood.

In severe cases low sodium levels can lead to seizures thoughts about harming yourself or ending your life eye pain, a change in your eyesight, or swelling or redness in or around the eye severe constipation or you're unable to pee and it's causing severe stomach pain Call now if you get: weakness on one side of your body trouble speaking or thinking loss of balance, or blurred eyesight These can be signs of a stroke.

If you suspect that you or someone else is having a stroke, phone immediately and ask for an ambulance Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to dosulepin. Information: You can report any suspected side effect using the Yellow Card safety scheme. Visit Yellow Card for further information. What to do about: constipation — eat more high-fibre foods, such as fresh fruit and vegetables and cereals.

Try to have several glasses of water or other non-alcoholic drinks every day. If you can, it may also help to do some exercise. Watch a short video on how to treat constipation. Drink plenty of water or a non-alcoholic drink. Do not stand up too quickly after sitting or lying down.

Do not drive or use tools or machinery if you're feeling sleepy. If this doesn't help, talk to your doctor. Do not try to force the flow of urine. If you can't go, try again later. Talk to your doctor urgently if you can't pee at all. Do not drink too much alcohol. Talk to your doctor if the headaches last longer than a week or are severe.

Dosulepin and breastfeeding If your doctor or health visitor says your baby is healthy, dosulepin can be used during breastfeeding. It is important to continue taking dosulepin to keep you well. Breastfeeding will also benefit both you and your baby. Non-urgent advice: Tell your doctor if you're:. Mixing dosulepin with herbal remedies and supplements Do not take St John's wort, a herbal remedy for depression, while you're taking dosulepin.

Important: Medicine safety Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. How does dosulepin work? When will I feel better? How will it make me feel? How long will I take it for?

Why is dosulepin prescribed less often now? If it's not recommended, should I stop taking it? Can I still get dosulepin if it helps my depression? How does it compare with other antidepressants? Can I still get dosulepin if it helps my pain?

Other possible treatments include: painkillers like paracetamol or co-codamol some antidepressants that also help with pain, such as amitriptyline medicines that are usually used for epilepsy, such as pregabalin medicines that are usually used to treat high blood pressure, such as bisoprolol physiotherapy Finding the most suitable treatment depends on how long you have had the pain, your symptoms, and what medicines have and have not worked for you in the past. Is it safe to take for a long time?

The following information describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. Note: Montelukast also comes in other forms: chewable tablets and oral granules. This article only addresses the mg oral tablet form. This should be taken at about the same time each day. This is the dosage for adults as well as adolescents age 15 years and older.

This once-daily dosage for allergies applies for both seasonal allergic rhinitis and perennial allergic rhinitis. With seasonal allergic rhinitis, allergy symptoms occur only during certain seasons most commonly spring, summer, or early fall. And with perennial allergic rhinitis, allergy symptoms occur year-round, possibly every day. This is the dosage for adults and adolescents ages 15 years and older. Note: The manufacturer of montelukast oral tablets recommends taking the drug in the evening to treat asthma.

Make sure to take your dose at the time of day recommended by your doctor. This is the dosage for adults as well as adolescents ages 15 years and older. And if you already take montelukast oral tablet once daily for asthma or allergies, you should not take an extra dose before exercising.

Your doctor may prescribe montelukast oral tablets to treat both conditions. The usual dosage for adolescents ages 15 years and older is the same as it is for adults: one mg tablet once per day. Note: Montelukast also comes in other forms, including chewable tablets and oral granules. If you miss a dose of montelukast oral tablets, you should skip the missed dose.

Just take your next dose at your regular time. This can include setting an alarm or downloading a reminder app. A kitchen timer can work, too. Montelukast oral tablets are meant to be used as a long-term treatment. The Food and Drug Administration FDA approves prescription drugs such as montelukast oral tablets to treat certain conditions. Montelukast oral tablets may also be used off-label for other conditions. Allergic rhinitis may also be called hay fever. It develops when your immune system overreacts to something in the environment.

Montelukast oral tablets are used to treat two types of allergic rhinitis:. These other forms come in strengths that are approved for younger children with allergies. This article only addresses the milligram oral tablet form. Clinical studies have shown that montelukast oral tablets are an effective treatment for reducing allergic rhinitis symptoms. If you have questions about whether montelukast oral tablets are right for you, talk with your doctor.

Montelukast oral tablets are used to treat or help prevent symptoms of chronic asthma in adults and adolescents ages 15 years and older. Asthma causes inflammation swelling and damage and narrowing inside your airways. Symptoms can include:. An asthma attack occurs when these symptoms suddenly become severe. Instead, the drug works to help prevent chronic reoccurring symptoms of asthma, and may help prevent asthma attacks.

If you have asthma, talk with your doctor about your asthma treatment plan. Clinical studies have shown that montelukast oral tablets are an effective treatment for controlling asthma. You and your doctor will develop a personalized asthma care plan. This plan will include strategies to help prevent symptoms, such as avoiding certain triggers. According to treatment guidelines from the Global Initiative for Asthma, montelukast oral tablets are recommended as a second-choice treatment option.

First-line treatment options usually include low-dose inhaled corticosteroids , such as fluticasone Flovent. If you have questions about whether montelukast oral tablets are right for your asthma treatment, talk with your doctor. Montelukast oral tablets are used to help prevent acute exercise-induced bronchoconstriction EIB.

For this purpose, montelukast oral tablets can be used in adults as well as adolescents ages 15 years and older. Some people with asthma notice that their symptoms get worse when they exercise. Physical activity, especially in cold weather, commonly triggers asthma symptoms. Heavy breathing during exercise naturally causes bronchoconstriction narrowing of the airways to the lungs.

This can lead to severe shortness of breath, wheezing , coughing, and chest tightness in people with asthma. Strenuous exercise, such as running or playing sports, can also lead to dehydration and dryness in your airways.

This can also worsen EIB symptoms. Clinical studies have shown that montelukast oral tablets are an effective treatment for helping to prevent EIB. If you have asthma with EIB, you and your doctor will develop a personalized asthma care plan. Montelukast also comes in other forms, specifically chewable tablets and oral granules. Montelukast oral tablets are usually prescribed as part of an asthma or allergy care plan. This plan will include:. In addition to montelukast oral tablets, other maintenance or preventive medications for allergic rhinitis may include:.

This is usually a quick-acting bronchodilator a drug that rapidly relaxes your airways. Examples include:. Montelukast oral tablets are not a rescue treatment. If you have questions about using other drugs with montelukast oral tablets, talk with your doctor or pharmacist.

Montelukast is classified as a leukotriene receptor antagonist. Steroid treatments for asthma , such as prednisone , may cause weight gain or increased blood pressure.

Sodium is an inactive ingredient that helps the drug dissolve and be absorbed into your body. If you have high blood pressure or edema excess fluid in your body , your doctor may have told you to limit your sodium intake. Talk with your doctor or pharmacist if you have concerns about weight gain or increased blood pressure with montelukast oral tablets.

If you have questions about COPD treatments, talk with your doctor. Rarely, there have been reports of serious mood and behavior problems in people who took montelukast. These were mostly reported during montelukast treatment, but some were reported after the drug was stopped. If you or those around you notice any changes in your mood or behavior after you stop taking montelukast, call your doctor right away.

They may suggest other treatments for your condition. Montelukast oral tablets are small tablets that are either round or square-shaped. The color and markings on the tablet can vary depending on the manufacturer of the drug. Hives, also called urticaria, are raised, itchy skin welts.

They may appear lighter, darker, or redder than your usual skin tone. Montelukast oral tablets are sometimes prescribed off-label for hives. In , researchers reviewed 10 clinical studies of montelukast for chronic hives. There are no known interactions between montelukast oral tablets and alcohol.

But drinking a lot of alcohol while taking montelukast oral tablets may increase your risk for liver issues. Also, some research suggests that sulfites and histamines which are present in certain alcoholic beverages could potentially contribute to an asthma attack. If you drink alcohol, talk with your doctor about how much alcohol is safe for you to have while taking montelukast oral tablets.

Bile is a fluid produced by your liver that helps to digest fats in your food. This can lead to hepatitis. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works.

Other interactions can increase side effects or make them more severe. Before using montelukast, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use.



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